Authors:
Mary Eva McClure, PharmD
Tavajay Campbell, PharmD, BCACP, CDCES

Reviewers:
Michael Brodeur, PharmD, BCGP
Stuart T Haines, PharmD, BCACP, BCPS

Citation:
Carr DB, Beyene K, Doherty J, et al. Medication and Road Test Performance Among Cognitively Healthy Older Adults. JAMA Network Open 2023; 6(9): e2335651.

The Problem

While driving autonomy plays a crucial role in supporting mobility, social connections, and access to healthcare, older adults face elevated risks on the road.1 In 2020, roughly 7,500 older adults lost their lives in traffic accidents, with nearly 200,000 receiving medical treatment for injuries sustained in crashes.2  Moreover, based on the limited evidence and conventional methodology, it is difficult to determine the impact of adverse drug effects, medical conditions, and the interplay between both on crash risk in this population.  Health professionals often warn patients about the elevated risk of automotive accidents believed to be associated with sedatives and other drugs that may cause drowsiness or cognitive impairments. However, these recommendations are often based on “common sense” rather than empirical evidence.  Rigorously collected data would equip us to educate patients about potential dangers, help us engage in collaborative discussions with patients and providers about deprescribing, and improve road safety for this vulnerable demographic.

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