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Dec 16, 2011

Clinicians trying to make decisions based on the current best evidence are faced with an overwhelming obstacle, Too Much Information (TMI)! With over 25,000 new randomized controlled trials published each year how can a provider critically appraise these studies, determine their internal and external validity, put these results into context with what is already known, and then make an informed decision? Some of these data are biased and have uncertain value in patient care.

Comments: 3
Oct 20, 2011

Do you tell your patients to take levothyroxine in the morning 30 to 60 minutes before food and at least 4 hours apart from other medications?  It is well known that many medications and foods influence the absorption and distribution of thyroxine (T4).  Morning administration of levothyroxine, before meals and other medications, is recommended by expert consensus and the package insert

Comments: 2
Oct 18, 2010

Non-alcoholic fatty liver disease (NAFLD) is a condition characterized by fat deposition in the hepatocytes of patients with minimal or no alcohol intake.  NAFLD has emerged as the leading cause of chronic liver disease in the Western world, with an estimated prevalence of 20-30% in the general population.1  Patients with NAFLD may present along spectrum of histological findings, ranging from simple hepatic steatosis (fat accumulation without inflammation or fibrosis) to nonalcoholic steatohe

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