Aug 26, 2018

We now have two vaccinations to protect against herpes zoster — a live-attenuated vaccine (Zostavax) and the new recombinant subunit vaccine (Shingrix).

Comments: 0
Aug 3, 2018

Critically-evaluating the literature is essential to engage in evidence-based practice.  A key component of assessing studies involves determining whether the comparator groups are appropriate.  Most pharmacists are familiar with the use of placebos for evaluating drug treatments, but how many of us have considered the comparator groups in behavioral interventions?  For these situations, employing attention placebo controls (APC) is important in order to assure the comparator groups

Comments: 0
May 24, 2018

An estimated 1.2 million people in the United States are currently living with the human immunodeficiency virus-1 (HIV-1).1 There are currently no cures or vaccines to prevent HIV but the availability of antiretroviral therapy (ART) has significantly decreased HIV-associated morbidity and mortality.

Comments: 0
Mar 30, 2018

Obligatory comment on the current opioid epidemic: it’s bad…and getting worse.1,2 This problem is not a new one but even with increasing national awareness of this issue, the troubling truth is that opioid overdose deaths continue to increase from year to year.

Comments: 0
Mar 2, 2018

“You no longer need to take this medication” is music to a patient’s ears.  How often do clinicians have the opportunity to tell patients that stopping a medication is possible for a chronic condition?  A recently published study explores the possible benefits to discontinuing an alpha-1 blocker after receiving combination therapy with a 5-alpha reductase inhibitor for the treatment of benign prostatic hyperplasia (BPH).1


Comments: 0
Jan 5, 2018

We’ve all seen and used the American College of Cardiology 10-year atherosclerotic cardiovascular disease (ASCVD) risk calculator. There are several modifiable risk factors such as blood pressure, cholesterol, and smoking status that, if addressed, can lower ASCVD risk. But are there other modifiable risk factors that we are failing to account for and address? New evidence suggests systemic inflammation may be one.


Comments: 4
Jun 26, 2017

Among Medicare recipients, from 2000 to 2010, there was a whopping 83-fold increase (that’s an 8300% increase!) in the number of blood tests performed to determine their vitamin D status.1 What could possibly cause such a dramatic increase?  While the aging U.S.

Comments: 0
Mar 13, 2017

Could automated, web-based cognitive behavioral therapy (CBT) replace flesh-and-blood healthcare practitioners?  Can computers deliver healthcare at lower cost and similar quality to face-to-face interactions with humans? Several web-based CBT programs have been developed and are now being marketed directly to consumers.  But do they actually work?


Comments: 0
Feb 9, 2017

About 5 million Americans are currently living with heart failure (HF) and an astounding 24-42% of them also suffer from depression.1,2 One meta-analysis found a greater than 2-fold risk of death in patients with HF and comorbid depression.  Depressed patients with HF are more likely to be hospitalized, seek care from emergency rooms, and rack up big bills.3  Not surprisingly, patients with HF and depression have a much lower quality of life when compared to HF patients

Comments: 0
Jan 25, 2017

Critically evaluating the primary literature and applying the information to patient care is vital to ensuring optimal patient outcomes.  Unfortunately, the foundational knowledge and skills that most of us acquire during our formal education and post-graduate training programs are unlikely to fully prepare us for the challenges and intricacies of interpreting the evolving methods used in clinical drug studies today.  Like the development of any skill, it requires practice and refinement over

Comments: 5
Dec 29, 2016

When you reach a certain age, bowel cleansing becomes a necessary poison.  Colorectal cancer is the third most common type of cancer in the United States with an estimated 95,270 new colon and 39,220 new rectal cancer diagnoses for 2016. More importantly, colorectal cancer (CRC) is the second most common cause of cancer-related mortality in the United States.

Comments: 0
Aug 16, 2016

Persons diagnosed with a psychiatric disorder consume nearly half of all cigarettes smoked in the United States!  Moreover, they are at higher risk for premature death, especially from vascular disease and cancer.1  Smoking cessation efforts are paramount in this population but often more challenging.

Comments: 0
Jul 17, 2016

We're all aware that there is an obesity epidemic and its linked to dozens of health problems.1  But nothing we've done so far — public awareness campaigns, changes in school lunch programs, and approving new drugs for weight loss — has halted this epidemic.  Although the rate of obesity in kids age 2 to 19 has plateaued around 17%, it continues to climb in young adults and most of us keep packing on the pounds as we get older!2


Comments: 0
Jun 17, 2016

The list of regimens for Helicobacter pylori eradication is longer than ever.  In recent years, American and European guidelines have recommended clarithromycin-based triple therapy or bismuth-containing quadruple therapy for primary treatment of H.

Comments: 0
Apr 8, 2016

Managing behavioral health in persons with dementia is an enormous and growing problem. Today more than 5.3 million Americans are living with Alzheimer’s disease (AD) and that number is expected to increase by 30% by 2025.1 Most patients with AD have challenging neuropsychiatric symptoms such as agitation.

Comments: 0
Dec 31, 2015

Several studies have evaluated the correlation between low-dose aspirin and NSAID use and the development of colorectal cancer. In 2007, the U.S.

Comments: 0
Jul 18, 2015

Every health professional takes an oath to serve patients. To fulfill this covenant, patient trust must be earned. Without trust, patients are unlikely to share sensitive, personal information, hindering our ability to provide optimal care. Gaining trust is influenced by many factors. What influence does attire have on patients’ perceptions of their healthcare providers?


Comments: 7
Apr 3, 2014

Alzheimer Dementia (AD) is devastating and we need to start thinking outside the box with regard to treatment options. Currently available medications have only modest symptomatic benefits.1 Could something as widely available as vitamin E significantly alter the course of cognitive and functional decline invariable caused by AD?

Comments: 1
Feb 26, 2014

A simple fecal sample may be able to predict your patient’s risk for developing type 2 diabetes.  That’s right, not a blood test, but a STOOL test.   Our microbiome, the ecological community of microorganisms that share our bodies, influence our risk for disease.  And not just irritable bowel syndrome but many other diseases including type 2 diabetes, depression, cancer, asthma, psoriasis, and autism.1  Research regarding the connections between our microbiome and disease

Comments: 1
Feb 5, 2014

In the United States, nearly 70% of adults are overweight or obese.1  Excess adipose tissue increases the likelihood of developing sleep apnea, type 2 diabetes mellitus (T2DM), dyslipidemia, and hypertension. The rate of all-cause mortality in obese individuals is higher when compared to normal weight individuals.2 Its imperative that we address body weight with all patients in all health care settings – but particularly in primary care settings.

Comments: 1
Jun 14, 2013

Millions of Americans take a multivitamin daily. Millions do not. Should healthcare providers recommend a daily multivitamin to patients who do not already take one? Or discourage those who do?

Comments: 0
May 23, 2013

The World Health Organization (WHO) estimates that only 53% of pregnant women worldwide received any antiretrovirals during pregnancy to prevent mother-to-child HIV transmission in 2009.  In the absence of any intervention, the risk of transmission is high (upto 45%).1  Therefore it is crucial that infants born to previously untreated mothers receive postexposure prophylaxis.

Comments: 0
Mar 27, 2013

The CONQUER study was double-blind, placebo-controlled clinical trial that examined the potential benefits of the combination product Qsymia (phenterimine and topiramate) in patients who were overweight and obese.  Our moderator and panelists explore the findings of this study and how this new information should be applied to practice.

Comments: 0
Mar 29, 2012

Dronedarone (Multaq®), a guideline recommended drug therapy option for paroxysmal and persistent atrial fibrillation (AF), has failed to deliver on the initial hopes and hype as the safer alternative to amiodarone.  Recent studies have shown that dronedarone is associated with severe liver injury, pulmonary fibrosis, pneumonitis, as well as an increased risk of stroke and death.1-6 With the addition of a boxed warning prohibiting its use in patients with permanent AF, dronedarone m

Comments: 1